Breakdown of hardly degradable carbohydrates (lignocellulose) in a two-stage anaerobic digestion plant is favored in the main fermenter

Heyer, Robert; Hellwig, Patrick; Maus, Irena; Walke, Danile; Schlüter, Andreas; Hassa, Julia; Sczyrba, Alexander; Tubbesing, Tom; Klocke, Michael; Mächtig, Torsten; Schallert, Kay; Seick, Ingolf; Reichl, Udo; Benndorf, Dirk

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Improved biological methanation using tubular foam-bed reactor

Khesali Aghtaei, Hoda; Hyer, Robert; Reichl, Udo; Benndorf, Dirk

In: Biotechnology for biofuels and bioproducts - London : BioMed Central, Bd. 17 (2024), Artikel 66, insges. 12 S.

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Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle "OP7"

Rüdiger, Daniel; Piasecka, Julita; Küchler, Jan; Pontes, Carolina; Laske, Tanja; Kupke, Sascha Y.; Reichl, Udo

In: iScience - Amsterdam : Elsevier, Bd. 27 (2024), Heft 4, Artikel 109421, insges. 22 S.

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Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration

Göbel, Sven; Pelz, Lars; Silva, Cristina A. T.; Brühlmann, Béla; Hill, Charles; Altomonte, Jennifer; Kamen, Amine; Reichl, Udo; Genzel, Yvonne

In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 108 (2024), Artikel 240, insges. 18 S.

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From single-cell cloning to high-yield influenza virus production - implementing advanced technologies in vaccine process development

Zinnecker, Tilia; Badri, Najd; Araujo, Diogo; Thiele, Kristin; Reichl, Udo; Genzel, Yvonne

In: Engineering in life sciences - Weinheim : Wiley-VCH . - 2024, insges. 14 S. [Online first]

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Model-based optimization of cell-free enzyme cascades exemplified for the production of GDP-fucose

Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Rexer, Thomas; Reichl, Udo; Klamt, Steffen

In: Metabolic engineering - Orlando, Fla. : Academic Press, Bd. 81 (2024), S. 10-25

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Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity

Karsten, Christina B.; Buettner, Falk F.R.; Cajic, Samanta; Nehlmeier, Inga; Roshani, Berit; Klippert, Antonina; Sauermann, Ulrike; Stolte-Leeb, Nicole; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christine

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Adjuvanted SARS-CoV-2 spike protein vaccination with altered glycosylation elicits improved TH1 humoral and cellular immunity in mice

Rudert, J.; Bälkner, M.; Juarez-Osorio, M.; Rexer, T.; Reichl, Udo; Jacobsen, H.; Metzdorf, K.; Bruder, D.; Volckmar, J.

In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft S2, S. 358, Artikel P376 [Konferenz: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), Strasbourg, France, 26-29 September 2023]

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Degradation kinetics of lignocellulolytic enzymes in a biogas reactor using quantitative mass spectrometry

Küchler, Jan; Willenbücher, Katharina; Reiß, Elisabeth; Nuß, Lea; Conrady, Marius; Ramm, Patrice; Schimpf, Ulrike; Reichl, Udo; Szewzyk, Ulrich; Benndorf, Dirk

In: Fermentation - Basel : MDPI, Bd. 9 (2023), Heft 1, Artikel 67, 1 Online-Ressource (12 Seiten)

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Upstream processing for viral vaccines - general aspects

Pelz, Lars; Göbel, Sven; Jaen, Karim; Reichl, Udo; Genzel, Yvonne

In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 79-135

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Upstream processing for viral vaccines - process intensification

Göbel, Sven; Pelz, Lars; Reichl, Udo; Genzel, Yvonne

In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 137-173

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Production of retroviral vectors in continuous high cell density culture

Hein, Marc D.; Kazenmaier, Daniel; van Heuvel, Yasemin; Dogra, Tanya; Cattaneo, Maurizio; Kupke, Sascha Y.; Stitz, Jörn; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 107 (2023), S. 5947-5961

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Cell-free biosynthesis meets dynamic optimization and control - a fed-batch framework

Espinel-Ríos, Sebastián; Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Morabito, Bruno; Rexer, Thomas F. T.; Reichl, Udo; Klamt, Steffen; Findeisen, Rolf

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Reliable N-glycan analysis - removal of frequently occurring oligosaccharide impurities by enzymatic degradation

Burock, Robert; Cajic, Samanta; Henning, René; Buettner, Falk, F. R.; Reichl, Udo; Rapp, Erdmann

In: Molecules - Basel : MDPI, Bd. 28 (2023), Heft 4, Artikel 1843, insges. 19 S.

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Process intensification strategies toward cell culture-based high-yield production of a fusogenic oncolytic virus

Göbel, Sven; Jaén, Karim E.; Dorn, Marie; Neumeyer, Victoria; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne

In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley . - 2023, insges. 19 S.

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Generation of "OP7 chimera" defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice

Dogra, Tanya; Pelz, Lars; Boehme, Julia D.; Kuechler, Jan; Kershaw, Olivia; Marichal-Gallardo, Pável Alejandro; Baelkner, Maike; Hein, Marc Dominique; Gruber, Achim; Benndorf, Dirk; Genzel, Yvonne; Bruder, Dunja; Kupke, Sascha Young; Reichl, Udo

In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 13 (2023), Artikel 20936, insges. 13 S.

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A cell-free multi-enzyme cascade reaction for the synthesis of CDP-glycerol

Alcalá-Orozco, E. Alberto; Grote, Valerian; Fiebig, Timm; Klamt, Steffen; Reichl, Udo; Rexer, Thomas

In: ChemBioChem - Weinheim : Wiley-VCH . - 2023, Artikel e202300463 [Early view]

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Cell-free N-glycosylation of peptides using synthetic lipid-linked hybrid and complex N-glycans

Wenzel, Lisa; Hoffmann, Marcus; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo

In: Frontiers in molecular biosciences - Lausanne : Frontiers, Bd. 10 (2023), insges. 11 S.

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Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus

Göbel, Sven; Jaén, Karim E.; Fernandes, Rita P.; Reiter, Manfred; Altomonte, Jennifer; Reichl, Udo; Genzel, Yvonne

In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley . - 2023, insges. 12 S. [Early view]

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Removable Ddes - the missing link for in-depth N-glycan analysis via multi-method approaches

Cajic, Samanta; Hennig, René; Grote, Valerian; Reichl, Udo; Rapp, Erdmann

In: Engineering - Beijing : Engineering Sciences Press., Bd. 26 (2023), S. 132-150

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Broad-spectrum antiviral activity of influenza A Defective Interfering Particles against respiratory syncytial, yellow fever, and Zika virus replication in vitro

Pelz, Lars; Piagnani, Elena; Marsall, Patrick; Wynserski, Nancy; Hein, Marc Dominique; Marichal-Gallardo, Pavel; Kupke, Sascha Young; Reichl, Udo

In: Viruses - Basel : MDPI, Bd. 15 (2023), Heft 9, Artikel 1872, insges. 17 S.

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Absolute quantification of viral proteins during single-round replication of MDCK suspension cells

Küchler, Jan; Püttker, Sebastian; Lahmann, Patrick; Genzel, Yvonne; Kupke, Sascha; Benndorf, Dirk; Reichl, Udo

In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 259 (2022), Artikel 104544, insges. 10 S.

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Discovering biomarkers for non-alcoholic steatohepatitis patients with and without hepatocellular carcinoma using fecal metaproteomics

Sydor, Svenja; Dandyk, Christian; Schwerdt, Johannes; Manka, Paul; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Wolf, Maximilian; Reichl, Udo; Canbay, Ali E.; Bechmann, Lars P.; Heyer, Robert

In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 16, Artikel 8841, insges. 14 S.

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Adaptation of a microbial community to demand-oriented biological methanation

Khesali Aghtaei, Hoda; Püttker, Sebastian; Maus, Irena; Heyer, Robert; Huang, Liren; Sczyrba, Alexander; Reichl, Udo; Benndorf, Dirk

In: Biotechnology for biofuels and bioproducts - London : BioMed Central, Bd. 15 (2022), Heft 1, Artikel 125, 1 Online-Ressource (19 Seiten)

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High-titer hepatitis C virus production in a scalable single-use high cell density bioreactor

Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Venkatesan, Nadini Prabhakar; Krarup, Henrik; Lin, Xiangliang; Reichl, Udo; Bukh, Jens; Genzel, Yvonnne; Gottwein, Judith Margarete

In: Vaccines - Basel : MDPI, Bd. 10 (2022), Heft 2, Artikel 249, insges. 24 S.

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Human 3D airway tissue models for real-time microscopy - visualizing respiratory virus spreading

Möckel, Marion; Baldok, Nino; Walles, Thorsten; Hartig, Roland; Müller, Andreas Johann; Reichl, Udo; Genzel, Yvonne; Walles, Heike; Wiese-Rischke, Cornelia

In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 22, Artikel 3634, insges. 21 S.

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Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures

Göbel, Sven; Kortum, Fabian; Chavez, Karim Jaén; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne

In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 106 (2022), Heft 13/16, S. 4945-4961

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Impact of influenza A virus infection on growth and metabolism of suspension MDCK cells using a dynamic model

Ramos, João Rodrigues Correia; Bissinger, Thomas; Genzel, Yvonne; Reichl, Udo

In: Metabolites - Basel : MDPI, Bd. 12 (2022), Heft 3, Artikel 239, insges. 27 S.

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Cell culture-based production of influenza A virus-derived defective interfering particles

Hein, Marc Dominique; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XV, 98, XVII-L Seiten, 5,1 MB) [Literaturverzeichnis: Seite XX-XXXVII]

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Development of chromatography-based purification processes for cell culture-derived influenza virus particles

Weigel, Thomas; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XXII, 145 Seiten, 2,22 MB) [Literaturverzeichnis: Seite 119-133]

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Mathematical models of influenza A virus infection - multiplicity of infection and its impact on co-infection and virus production

Rüdiger, Daniel; Tsotsas, Evangelos; Reichl, Udo

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Fecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss

Biemann, Ronald; Buß, Enrico; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Püttker, Sebastian; Reichl, Udo; Isermann, Berend; Schneider, Jochen; Saake, Gunter; Heyer, Robert

In: Biomolecules - Basel : MDPI - Vol.11.2021, 5, 726, insgesamt 13 Seiten

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Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins

Pech, Sabine; Rehberg, Markus; Janke, Robert; Benndorf, Dirk; Genzel, Yvonne; Muth, Thilo; Sickmann, Albert; Rapp, Erdmann; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), S. 1861-1874

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Preface

Rapp, Erdmann; Reichl, Udo

In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. v-vi

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Correction to: Animal Cell Expression Systems

Butler, M.; Reichl, Udo

In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. 459-461

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Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans

Chuzel, Léa; Fossa, Samantha L.; Boisvert, Madison L.; Cajic, Samanta; Heenig, René; Ganatra, Mehul B.; Reichl, Udo; Rapp, Erdmann; Taron, Christopher H.

In: Microbial cell factories - London: Biomed Central, Bd. 20 (2021), S. 1-17

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Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity

Rand, Ulfert; Kupke, Sascha Young; Shkarlet, Hanna; Hein, Marc Dominique; Hirsch, Tatjana; Marichal-Gallardo, Pável Alejandro; Cicin-Sain, Luka; Reichl, Udo; Bruder, Dunja

In: Cells - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 14 S.

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SARS-CoV-2 production in a scalable high cell density bioreactor

Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Costa, Rui; Venkatesan, Nandine Prabhakar; Lin, Xiangliang; Pham, Long Van; Feng, Shan; Fahnøe, Ulrik; Scheel, Troels Kasper Høyer; Ramirez, Santseharay; Reichl, Udo; Bukh, Jens; Genzel, Yvonne; Gottwein, Judith Margarete

In: Vaccines - Basel: MDPI, Bd. 9 (2021), 7

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OP7, a novel influenza A virus defective interfering particle - production, purification, and animal experiments demonstrating antiviral potential

Hein, Marc D.; Kollmus, Heike; Marichal-Gallardo, Pavel; Püttker, Sebastian; Benndorf, Dirk; Genzel, Yvonne; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin : Springer , 1975, Bd. 105 (2021), Heft 1, S. 129-146

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Comprehensive N‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells

Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Pioch, Markus; Hennig, René; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo

In: The FEBS journal / Vereinigung der Europäischen Biochemischen Gesellschaften - Oxford [u.a.] : Wiley-Blackwell, Bd. 288 (2021), Heft 16, S. 4869-4891

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Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins

Pralow, Alexander; Nikolay, Alexander; Leon, Arnaud; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo

In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 11 (2021), Artikel 5147

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Associated viral gene transfer vectors by membrane-based steric exclusion chromatography

Marichal-Gallardo, Pavel; Börner, Kathleen; Pieler, Michael M.; Sonntag-Buck, Vera; Obr, Martin; Bejarano, David; Wolff, Michael W.; Kräusslich, Hans-Georg; Reichl, Udo; Grimm, Dirk

In: Human gene therapy - New York, NY: Liebert, 2021, insgesamt 16 Seiten

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Critical Assessment of MetaProteome Investigation (CAMPI) - a multi-laboratory comparison of established workflows

Van Den Bossche, Tim; Kunath, Benoit J.; Schallert, Kay; Schäpe, Stephanie S.; Abraham, Paul C.; Armengaud, Jean; Arntzen, Magnus Ø.; Bassignani, Ariane; Benndorf, Dirk; Fuchs, Steohan; Giannone, Richard J.; Griffin, Timothy J.; Hagen, Live H.; Halder, Rashi; Henry, Céline; Hettich, Robert L.; Heyer, Robert; Jagtap, Pratik; Jehmlich, Nico; Jensen, Marlene; Juste, Ctherine; Kleiner, Manuel; Langella, Olivier; Lehmann, Theresa; Leith, Emma; May, Patrick; Mesuere, Bart; Miotello, Guylaine; Peters, Samantha L.; Pible, Olivier; Queiros, Pedro T.; Reichl, Udo; Renard, Bernhard Y.; Schiebenhoefer, Henning; Sczyrba, Alexander; Tanca, Alessandro; Trappe, Kathrin; Trezzi, jean-Pierre; Uzzau, Sergio; Verschaffelt, Pieter; Bergen, Martin von; Wilmes, Paul; Wolf, Maximilian; Martens, Lennart; Muth, Thilo

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Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select candidates for antiviral therapy

Pelz, Lars; Rüdiger, Daniel; Dogra, Tanya; Alnaji, Fadi G.; Genzel, Yvonne; Brooke, Christopher B.; Kupke, Sascha Y.; Reichl, Udo

In: Journal of virology - Baltimore, Md.: Soc., Bd. 95 (2021), 24, insges. 18 S.

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Cell-free multi-enzyme synthesis and purification of uridine diphosphate galactose

Mahour, Reza; Lee, Ju Weon; Grimpe, Pia; Boecker, Simon; Grote, Valerian; Klamt, Steffen; Seidel-Morgenstern, Andreas; Rexer, Thomas F. T.; Reichl, Udo

In: ChemBioChem - Weinheim: Wiley-VCH, Bd. 22 (2021), S. 1-11

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Forschungsarbeiten am Institut für Verfahrenstechnik der OttovonGuerickeUniversität Magdeburg

Reichl, Udo; Seidel-Morgenstern, Andreas; Sundmacher, Kai; Tsotsas, Evangelos; Wachem, Berend

In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 93 (2021), Heft 3, S. 345-352

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Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles

Hein, Marc D.; Arora, Prerna; Marichal-Gallardo, Pável Alejandro; Winkler, Michael; Genzel, Yvonne; Pöhlmann, Stefan; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo

In: BMC biology - Berlin: Springer, Bd. 19 (2021)

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MPA_Pathway_Tool - user-friendly, automatic assignment of microbial community data on metabolic pathways

Walke, Daniel; Schallert, Kay; Ramesh, Prasanna; Benndorf, Dirk; Lange, Emanuel; Reichl, Udo; Heyer, Robert

In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 22 (2021), Heft 20, Artikel 10992, insges. 12 S.

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Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography

Fortuna, Raquel A.; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo

In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 342 (2021), S. 139-148

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Multienzyme cascades for the in vitro synthesis of guanosine diphosphate Lfucose

Mahour, Reza; Marichal-Gallardo, Pavel A.; Rexer, Thomas; Reichl, Udo

In: ChemCatChem - Weinheim: WILEY-VCH Verlag, Bd. 13 (2021), insges. 11 S.

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A high cell density perfusion process for Modified Vaccinia virus Ankara production - process integration with inline DNA digestion and cost analysis

Gränicher, Gwendal; Babakhani, Masoud; Göbel, Sven; Jordan, Ingo; Marichal-Gallardo, Pavel; Genzel, Yvonne; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2021, insges. 15 S.

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Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein

Ruhnau, Johannes; Grote, Valerian; Juarez-Osorio, Mariana; Bruder, Dunja; Mahour, Reza; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo

In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 10 S.

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Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

Hein, Marc D.; Chawla, Anshika; Cattaneo, Maurizio; Kupke, Sascha Y.; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), S. 72517264

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Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture

Rüdiger, Daniel; Pelz, Lars; Hein, Marc D.; Kupke, Sascha Y.; Reichl, Udo

In: PLoS Computational Biology/ Public Library of Science - San Francisco, Calif.: Public Library of Science, Bd. 17 (2021), 9, insges. 28 S.

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Integrated cycles for urban biomass as a strategy to promote a CO2-neutral society - a feasibility study

Meinusch, Nicole; Kramer, Susanne; Körner, Oliver; Wiese, Jürgen; Seick, Ingolf; Beblek, Anita; Berges, Regine; Illenberger, Bernhard; Illenberger, Marco; Uebbing, Jennifer; Wolf, Maximilian; Saake, Gunter; Benndorf, Dirk; Reichl, Udo; Heyer, Robert

In: Sustainability - Basel : MDPI, Bd. 13 (2021), Heft 17, Artikel 9505, insges. 22 S.

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Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells

Bissinger, Thomas; Wu, Yixiao; Marichal-Gallardo, Pável Alejandro; Riedel, Dietmar; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, Bd. 118 (2021), 10, S. 3996-4013

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High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells

Wu, Yixiao; Bissinger, Thomas; Genzel, Yvonne; Liu, Xuping; Reichl, Udo; Tan, Wen-Song

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), 4, S. 1421-1434

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Process intensification for the production of MVA and influenza A virus in high density suspension cultures of AGE1.CR.pIX cells

Vázquez Ramírez, Daniel; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XIV, 136 Seiten, 7,58 MB), Illustrationen

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Scalable multi-enzyme platforms for the in vitro glycoengineering of therapeutic proteins & synthesis of human milk oligosaccharides

Mahour, Reza; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, 2022, 1 Online-Ressource (XV, 170 Blätter, 5,8 MB), Illustrationen

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Application of functional metagenomics to the field of glycobiology

Chuzel, Léa; Reichl, Udo

In: Düren: Shaker Verlag, 2022, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2021, XI, 229 Seiten - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; Band 55), ISBN: 3-8440-8437-1 [Literaturverzeichnis: Seite 186-210]

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Process intensification and integration for the production of vaccines and viral vectors

Gränicher, Gwendal; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XXX, 222 Seiten, 8,49 MB), Illustrationen, Diagramme

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Mathematical models of influenza A virus infection - elucidating the impact of host cell factors and defective interfering particles on virus growth

Laske, Tanja; Sundmacher, Kai; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XVIII, 233 Seiten, 17,07 MB), Illustrationen, Diagramme

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Metaproteomanalyse methanogener Mikrobiome aus Anreicherungskulturen im Labormaßstab

Kohrs, Fabian; Reichl, Udo

In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (IX, 123, A-J Seiten, 3,84 MB), Illustrationen

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Advances in glycobiotechnology

Rapp, Erdmann; Reichl, Udo

In: Cham: Springer, 2021, viii, 461 Seiten - (Advances in biochemical engineering/biotechnology; 175), ISBN: 978-3-030-69589-7

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Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides

Rexer, Thomas F. T.; Wenzel, Lisa; Hoffmann, Marcus; Tischlik, Sebastian; Bergmann, Christin; Grote, Valerian; Boecker, Simon Matthias; Bettenbrock, Katja; Schildbach, Anna; Kottler, Robert; Mahour, Reza; Rapp, Erdmann; Pietzsch, Markus; Reichl, Udo

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Impact of feeding and stirring regimes on the internal stratification of microbial communities in the fermenter of anaerobic digestion plants

Heyer, Robert; Klang, Johanna; Hellwig, Patrick; Schallert, Kay; Kress, Philipp; Hülsemann, Benedikt; Theuerl, Susanne; Reichl, Udo; Benndorf, Dirk

In: Bioresource technology - Amsterdam [u.a.] : Elsevier Science - 314(2020), Artikel-Nummer 123679, 1 Online-Ressource

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Perfusion control for high cell density cultivation and viral vaccine production

Nikolay, Alexander; Bissinger, Thomas; Gränicher, Gwendal; Wu, Yixiao; Genzel, Yvonne; Reichl, Udo

In: Animal Cell Biotechnology: Methods and Protocols - New York, NY: Springer US; Pörtner, Ralf . - 2020, S. 141-168

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Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus replication

Kupke, Sascha Young; Ly, Lam-Ha; Börno, Stefan Thomas; Ruff, Alexander; Timmermann, Bernd; Vingron, Martin; Haas, Stefan; Reichl, Udo

In: Viruses - Basel: MDPI, 12 (2020,1), Artikelnummer 71, 19 Seiten

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Production of Modified Vaccinia Ankara virus by intensified cell cultures - a comparison of platform technologies for viral vector production

Gränicher, Gwendal; Tapia, Felipe; Behrendt, Ilona; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo

In: Biotechnology journal - Weinheim: Wiley-VCH, Bd. 16 (2021), 1, insges. 10 S., 2020

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Application of an nnclined settler for cell culture-based influenza A virus production in perfusion mode

Coronel, Juliana; Gränicher, Gwendal; Sandig, Volker; Noll, Thomas; Genzel, Yvonne; Reichl, Udo

In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, Volume 8 (2020), article 672, insgesmat 13 Seiten

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Virus harvesting in perfusion culture - choosing the right type of hollow fiber membrane

Nikolay, Alexander; Grooth, Joris; Genzel, Yvonne; Wood, Jeffery A.; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, 2020, insgesamt 13 Seiten[Online first]

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Performance of an acoustic settler versus a hollow fiberbased ATF technology for influenza virus production in perfusion

Gränicher, Gwendal; Coronel, Juliana; Trampler, Felix; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 104.2020, S. 4877-4888

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A dynamic model linking cell growth to intracellular metabolism and extracellular byproduct accumulation

Ramos, João R.; Rath, Alexander G.; Genzel, Yvonne; Sandig, Volker; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2020, insges. 21 S.

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Single-cell analysis of influenza A virus replication - sources of cell-to-cell heterogeneity and discoverey of a novel type of defective interfering particle

Kupke, Sascha Young; Reichl, Udo

In: Magdeburg, 2020, XV, 155 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 122-136]

Evaluation of MDCK suspension cell lines for influenza A virus production - media, metabolism, and process conditions

Bissinger, Thomas; Reichl, Udo

In: Magdeburg, 2020, XXVI, 137 Seiten, Illustrationen, Diagramme, 30 cm

In-depth mass spectrometry-based glycoproteomics - advances in sample preparation, measurement and data-analysis of glycoproteins

Hoffmann, Marcus; Reichl, Udo; Rapp, Erdmann

In: Magdeburg, 2020, XI, 141 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 118-133]

Intensified yellow fever and Zika virus production in animal cell culture

Nikolay, Alexander; Reichl, Udo

In: Magdeburg, 2020, XV, 175 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 139-157]

Dialyseinduzierte Veränderungen im menschlichen Serum-Protein N-Glykosylation

Lindquist, Jonathan; Hennig, René; Rapp, Erdmann; Reichl, Udo; Mertens, Peter Rene

In: Kongress für Nephrologie, 11. Jahrestagung der Deutschen Gesellschaft für Nephrologie: Die Nephrologie als ganzheitliche Disziplin in der Patientenversorgung : 10. 13. Oktober 2019 in Düsseldorf : Programm/ Kongress für Nephrologie, 2019, P256, S. 165

RedCom - a strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion

Koch, Sabine; Kohrs, Fabian; Lahmann, Patrick; Bissinger, Thomas; Wendschuh, Stefan; Benndorf, Dirk; Reichl, Udo

In: PLoS Computational Biology / Public Library of Science - San Francisco, Calif. : Public Library of Science - Vol. 15 (2019), 2, Artikel e1006759, insgesamt 32 Seiten

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Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis

Lehmann, Tony; Schallert, Kay; Vilchez-Vargas, Ramiro; Benndorf, Dirk; Püttker, Sebastian; Sydor, Svenja; Schulz, Christian; Bechmann, Lars Peter; Canbay, Ali E.; Heidrich, Benjamin; Reichl, Udo; Link, Alexander; Heyer, Robert

In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 201 (2019), S. 93-103

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A robust and universal metaproteomics workflow for research studies and routine diagnostics within 24 h using phenol extraction, FASP digest, and the MetaProteomeAnalyzer

Heyer, Robert; Schallert, Kay; Büdel, Anja; Zoun, Roman; Dorl, Sebastian; Behne, Alexander; Kohrs, Fabian; Püttker, Sebastian; Siewert, Corina; Muth, Thilo; Saake, Gunter; Reichl, Udo; Benndorf, Dirk

In: Frontiers in microbiology - Lausanne : Frontiers Media - 10 (2019), article 1883, insgesamt 20 Seiten

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Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the von Magnus effect

Tapia Delgado, Felipe Ignacio; Wohlfahrth, Daniel; Sandig, Volker; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo

In: PLOS ONE - San Francisco, California, US: PLOS, 2006, 14 (2019), 11, article e0224317, insgesamt 21 Seiten

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Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems

Coronel, Juliana; Behrendt, Ilona; Bürgin, Tim; Anderlei, Tibor; Sandig, Volker; Reichl, Udo; Genzel, Yvonne

In: Vaccine - Amsterdam: Elsevier, Bd. 37.2019, 47, S. 7011-7018

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Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus productionPK2.1

Bissinger, Thomas; Fritsch, Johannes; Mihut, Adrian; Wu, Yxiao; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, Bd. 37 (2019), 47, S. 7003-7010

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Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1

Gränicher, Gwendal; Coronel, Juliana; Pralow, Alexander; Marichal-Gallardo, Pável Alejandro; Wolff, Michael; Rapp, Erdmann; Karlas, Alexander; Sandig, Volker; Genzel, Yvonne; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 37.2019, 47, S. 7019-7028

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Production of Defective Interfering Particles of influenza A virus in parallel continuous cultures at two residence times - insights from qPCR measurements and viral dynamics modeling

Tapia Delgado, Felipe Ignacio; Laske, Tanja; Wasik, Milena A.; Rammhold, Markus; Genzel, Yvonne; Reichl, Udo

In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Volume 7 (2019), Artikel 275, insgesamt 15 Seiten

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Enzymatic cascades for tailored 13 C 6 and 15 N enriched human milk oligosaccharides

Fischöder, Thomas; Cajic, Samanta; Grote, Valerian; Greifenstein, Raphael; Reichl, Udo; Franzreb, Matthias; Rapp, Erdmann; Elling, Lothar

In: Molecules: a journal of synthetic chemistry and natural product chemistry - Basel: MDPI, 1996, Volume 24 (2019), 19, Artikel 3482, insgesamt 21 Seiten

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Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses

Fortuna, A. Raquel; van Teeffelen, Sebastian; Ley, Adrian; Fischer, Laura M.; Taft, Florian; Genzel, Yvonne; Villain, Louis; Wolff, Michael W.; Reichl, Udo

In: Separation and purification technology - Amsterdam [u.a.]: Elsevier Science, 1997, Bd. 226.2019, S. 350-358

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Metaproteome analysis reveals that syntrophy, competition, and phage-host interaction shape microbial communities in biogas plants

Heyer, Robert; Schallert, Kay; Siewert, C.; Kohrs, F.; Greve, J.; Maus, I.; Klang, J.; Klocke, M.; Heiermann, M.; Hoffmann, Michael; Püttker, Sebastian; Calusinska, M.; Zoun, Roman; Saake, Gunter; Benndorf, Dirk; Reichl, Udo

In: Microbiome - London : Biomed Central, Bd. 7 (2019), Artikel 69, insges. 17 S.

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Hydrophobic-interaction chromatography for purification of influenza A and B virus

Weigel, Thomas; Soliman, Remon; Wolff, Michael W.; Reichl, Udo

In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, Bd. 1117.2019, S. 103-117

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High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system

Vázquez Ramírez, Daniel; Jordan, Ingo; Sandig, Volker; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 103 (2019), 7, S. 3025-3035

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A system for production of defective interfering particles in the absence of infectious influenza A virus

Bdeir, Najat; Arora, Prerna; Gärtner, Sabine; Hoffmann, Markus; Reichl, Udo; Pöhlmann, Stefan; Winkler, Michael

In: PLOS ONE - San Francisco, California, US: PLOS, Vol. 14.2019, 3, Artikel e0212757, insgesamt 18 Seiten

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Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGELIF based highthroughput analysis

Fischöder, Thomas; Cajic, Samanta; Reichl, Udo; Rapp, Erdmann; Elling, Lothar

In: Biotechnology journal - Weinheim: Wiley-VCH, Vol. 14 (2019), 3, Artikelnr. 1800305, insges. 9 Seiten

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A novel type of influenza a virus-derived defective interfering particle with nucleotide substitutions in its genome

Kupke, Sascha Young; Riedel, Dietmar; Frensing, Timo; Zmora, Pawel; Reichl, Udo

In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 93.2019, 4, Art.-Nr. e01786, insges. 24 Seiten

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High-throughput serum N-glycomics - method comparison and application to study rheumatoid arthritis and pregnancy-associated changes

Reiding, Karli R.; Bondt, Albert; Hennig, René; Gardner, Richard A.; O'Flaherty, Roisin; Trbojevič-Akmačič, Irena; Shubhakar, Archana; Hazes, Johanna M. W.; Reichl, Udo; Fernandes, Daryl L.; Pučič-Bakovič, Maja; Rapp, Erdmann; Spencer, Daniel I. R.; Dolhain, Radboud J. E. M.; Rudd, Pauline M.; Lauc, Gordon; Wuhrer, Manfred

In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 18.2019, 1, S. 3-15

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Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers

Marichal-Gallardo, Pável Alejandro; Reichl, Udo

In: Magdeburg, 2019, xiii, 118 Blätter, Illustrationen, Diagramme, 30 cm

Continuous upstream processing for cell culture-derived virus production

Tapia Delgado, Felipe Ignacio; Reichl, Udo

In: Magdeburg, 2019, xv, 112 Blätter, Illustrationen, Diagramme, 30 cm

Herstellungsprozess für onkolytische Masernviren

Grein, Tanja A.; Reichl, Udo

In: Düren: Shaker Verlag, 2019, XII, 195 Seiten, 24 Illustrationen, Diagramme, 21 cm, 314 g - (Schriftenreihe des Institutes für Bioverfahrenstechnik und Pharmazeutische Technologie; Band 15)

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Charakterisierung der Influenzavirus-Vermehrung in genetisch veränderten humanen Zelllinien zur Optimierung der Impfstoffproduktion

Bachmann, Mandy; Reichl, Udo

In: Magdeburg, 2019, XI, 173 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 133-155]

The fine art of destruction - a guide to indepth glycoproteomic analyses-exploiting the diagnostic potential of fragment ions

Hoffmann, Marcus; Pioch, Markus; Pralow, Alexander; Henning, René; Kottler, Robert; Reichl, Udo; Rapp, Erdmann

In: Proteomics - Weinheim: Wiley VCH, 2001, Vol. 18.2018, 24, Art.-Nr. 1800282

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glyXtoolMS - an open-source pipeline for semiautomated analysis of glycopeptide mass spectrometry data

Pioch, Markus; Hoffmann, Marcus; Prahlow, Alexander; Reichl, Udo; Rapp, Erdmann

In: Analytical chemistry: the authoritative voice of the analytical community - Columbus, Ohio: American Chemical Society, 1947, Bd. 90.2018, 20, S. 11908-11916

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A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures

Rüdiger, D.; Kupke, S. Y.; Reichl, Udo

In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 51.2018, 19, S. 32-33[Konferenz: 7th Conference on Foundation of Systems Biology in Engineering, FOSBE 2018, Chicago, Illinois, USA, 05-08 August 2018]

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Mathematical modeling as a tool to improve influenza vaccine production processes

Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Reichl, Udo; Kienle, Achim

In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier , 2015, Bd. 51 (2018), Heft 19, S. 1-4

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Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production

Nikolay, Alexander; Léon, Arnaud; Schwamborn, Klaus; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 20, S. 8725-8737

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Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells

Nikolay, Alexander; Castilho, Leda R.; Reichl, Udo; Genzel, Yvonne

In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 36.2018, 22, S. 3140-3145

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Purification of influenza viruslike particles using sulfated cellulose membrane adsorbers

Carvalho, Sofia B.; Fortuna, A. Raquel; Wolff, Michael W.; Peixoto, Cristina; Alves, Paula M.; Reichl, Udo

In: Journal of chemical technology & biotechnology - Chichester: Wiley, Bd. 93.2018, 7, S. 1988-1996[Special issue: Bioseparations]

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Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine

Mahour, Reza; Klapproth, Jan; Rexer, Thomas F. T.; Schildbach, Anna; Klamt, Steffen; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo

In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 283.2018, S. 120-129

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SDSPAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples

Wenzel, Lisa; Heyer, Robert; Schallert, Kay; Löser, Lucy; Wünschiers, Röbbe; Reichl, Udo; Benndorf, Dirk

In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 18 (2018), Heft 7, S. 498-509

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Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus

Vodovnik, Maša; Vrabec, Katja; Hellwig, Patrick; Benndorf, Dirk; Sežun, Mija; Gregori, Andrej; Gottumukkala, Lalitha D.; Anderson, Robin C.; Reichl, Udo

In: Journal of cleaner production - Amsterdam [u.a.]: Elsevier Science, Vol. 197.2018, Part 1, S. 253-263

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Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths

Fischer, Laura M.; Wolff, Michael; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, Bd. 36.2018, 22, S. 3153-3160

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High-cell-density cultivations to increase MVA virus production

Vázquez Ramírez, Daniel; Genzel, Yvonne; Jordan, Ingo; Sandig, Volker; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, Bd. 36 (2018), 22, S. 3124-3133

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Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers

Fortuna, Ana Raquel; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo

In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 18.2018, 1, S. 29-39

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Cell culture-based production of defective interfering particles for influenza antiviral therapy

Wasik, Milena A.; Eichwald, Luca; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 3, S. 1167-1177, 2017

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Improvement of electrospray stability in negative ion mode for nano-PGC-LC-MS glycoanalysis via post-column make-up flow

Nguyen-Khuong, Terry; Pralow, Alexander; Reichl, Udo; Rapp, Erdmann

In: Glycoconjugate journal: official journal of the International Glycoconjugate Organization - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 35.2018, 6, S. 499-509

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MPA portable - a stand-alone software package for analyzing metaproteome samples on the go

Muth, Thilo; Kohrs, Fabian; Heyer, Robert; Benndorf, Dirk; Rapp, Erdmann; Reichl, Udo; Martens, Lennart; Renard, Bernhard Y.

In: Analytical chemistry - Columbus, Ohio : American Chemical Society , 1947, Bd. 90 (2018), Heft 1, S. 685-689

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Animal cell expression systems

Butler, M.; Reichl, Udo

In: Advances in biochemical engineering, biotechnology - Berlin: Springer, S. 1-36, 2017[Online first]

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Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine

Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Rapp, Erdmann; Reichl, Udo

In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 7.2017, Art.-Nr. 11419, insgesamt 9 Seiten

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Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems

Tapia Delgado, Felipe Ignacio; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo

In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 12.2017, 8, Art.-Nr. e0182553, insges. 17 Seiten

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One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides

Rexer, Thomas F. T.; Schildbach, Anna; Klapproth, Jan; Schierhorn, Angelika; Mahour, Reza; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, Bd. 115 (2018), 1, S. 192-205

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Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol

Marichal-Gallardo, Pável Alejandro; Pieler, Michael M.; Wolff, Michael W.; Reichl, Udo

In: Journal of chromatography - New York, NY [u.a.] : Science Direct, Bd. 1483.2017, S. 110-119

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Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition

Kohrs, Fabian; Heyer, Robert; Bissinger, Thomas; Kottler, Robert; Schallert, Kay; Püttker, Sebastian; Behne, Alexander; Rapp, Erdmann; Benndorf, Dirk; Reichl, Udo

In: Anaerobe - London : Academic Press , 1995, Bd. 46 (2017), S. 56-68

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Specific ion effects on the particle size distributions of cell culturederived influenza A virus particles within the Hofmeister series

Pieler, Michael Martin; Heyse, Anja; Wolff, Michael Werner; Reichl, Udo

In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 5, S. 470-478

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Influence of the production system on the surface properties of influenza A virus particles

Hämmerlein, Frank; Pieler, Michael M.; Hennig, René; Serve, Anja; Rapp, Erdmann; Wolff, Michael W.; Reichl, Udo; Hubbuch, Jürgen

In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 10, S. 1071-1077

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Charakterisierung von mikrobiellen Gemeinschaften aus Biogasanlagen mittels Metaproteomanalyse und Korrelationen der Ergebnisse zu den Prozessparametern

Heyer, Robert Steven; Reichl, Udo

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, XVII, 164, xxxvii Blätter, Illustrationen

Characterisation of cell growth, metabolism and recombinant protein production during transient and steady state conditions for the human cell line AGE1.HN.AAT

Rath, Alexander; Sundmacher, Kai; Reichl, Udo

In: Magdeburg, 2017, XV, 178, xvi Seiten, Illustrationen, Diagramme, 30 cm

Investigation of influenza virus particle aggregation and purification with magnetic sulfated cellulose particles

Pieler, Michael Martin; Reichl, Udo

In: Magdeburg, 2017, xxv, 97 Seiten, Illustrationen

Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand

Meininger, M.; Stepath, M.; Hennig, R.; Cajic, S.; Rapp, E.; Rotering, H.; Wolff, M. W.; Reichl, Udo

In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, 1977, Bd. 1012/1013.2016, S. 193-203

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Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells

Frensing, Timo; Kupke, Sascha Young; Bachmann, Mandy; Fritzsche, Susanne; Gallo-Ramirez, Lili E.; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 100.2016, 16, S. 7181-7192

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Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs

Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo

In: Virus research : an international journal of molecular and cellular virology. - Amsterdam [u.a.] : Elsevier Science, Bd. 218.2016, S. 86-95

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Early changes in the metabolic profile of activated CD8+ T cells

Cammann, Clemens; Rath, Alexander; Reichl, Udo; Lingel, Holger; Brunner-Weinzierl, Monika; Simeoni, Luca; Schraven, Burkhart; Lindquist, Jonathan A.

In: BMC cell biology - London : BioMed Central - Bd. 17.2016, Art.-Nr. 28, insges. 11 S.

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Binding kinetics and multi-bond : finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces

Wang, Wenjing; Voigt, Andreas; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai

In: Analytical biochemistry : methods in the biological sciences. - San Diego, Calif : Elsevier, Bd. 505.2016, S. 8-17

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Metaproteomics applied to activated sludge for industrial wastewater treatment revealed a dominant methylotrophic metabolism of Hyphomicrobium zavarzinii

Salerno, Carlo; Benndorf, Dirk; Pech, Sabine; Palese, Luigi Leonardo; Reichl, Udo; Pollice, Alfieri

In: Microbial ecology - New York, NY: Springer . - 2016

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Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production

Tapia Delgado, Felipe Ignacio; Vázquez Ramírez, Daniel; Genzel, Yvonne; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 100 (2016), 5, S. 2121-2132

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Glycomic characterization of induced pluripotent stem cells derived from a patient suffering from phosphomannomutase 2 congenital Disorder of glycosylation (PMM2-CDG)

Thiesler, Christina T.; Cajic, Samanta; Hoffmann, Dirk; Thiel, Christian; Diepen, Laura van; Hennig, René; Sgodda, Malte; Weiβmann, Robert; Reichl, Udo; Steinemann, Doris; Diekmann, Ulf; Huber, Nicolas M. B.; Oberbeck, Astrid; Cantz, Tobias; Kuss, Andreas W.; Körner, Christian; Schambach, Axel; Rapp, Erdmann; Buettner, Falk F. R.

In: Molecular & cellular proteomics - Bethesda, Md. : The American Society for Biochemistry and Molecular Biology, Bd. 15 (2016), Heft 4, S. 1435-1452

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Impaired antiviral response of adenovirus-transformed cell lines supports virus replication

Bachmann, Mandy; Breitwieser, Theresa; Lipps, Christoph; Wirth, Dagmar; Jordan, Ingo; Reichl, Udo; Frensing, Timo

In: Journal of general virology: JGV - Reading: Soc., 1967, Bd. 97.2016, 2, S. 293-298

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Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process

Koch, Sabine; Benndorf, Dirk; Fronk, Karen; Reichl, Udo; Klamt, Steffen

In: Biotechnology for biofuels - London: BioMed Central, Bd. 9 (2016), 17, insges. 16 S.

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Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type

Heyer, Robert; Benndorf, Dirk; Kohrs, F.; Vrieze, J.; Boon, N.; Hoffmann, M.; Rapp, Erdmann; Schlüter, A.; Sczyrba, A.; Reichl, Udo

In: Biotechnology for biofuels - London: BioMed Central, Bd. 9 (2016), 1

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Diagnostic concept for dynamically operated biogas production plants

Bensmann, Astrid; Hanke-Rauschenbach, Richard; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Kausmann, Robert; Plöchl, Matthias; Heiermann, Monika; Reichl, Udo; Sundmacher, Kai

In: Renewable energy - Amsterdam [u.a.]: Elsevier Science, Vol. 96.2016, Part A, S. 479-489

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A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection

Pieler, Michael M.; Frentzel, Sarah; Bruder, Dunja; Wolff, Michael W.; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 34.2016, 50, S. 6367-6374

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Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells

Kluge, Sabine; Genzel, Yvonne; Laus, Kim; Serve, Anja; Pflugmacher, Antje; Peschel, Britta; Rapp, Erdmann; Reichl, Udo

In: Biotechnology journal : BTJ ; systems & synthetic biology, nanobiotech, medicine. - Weinheim : Wiley-VCH, Bd. 11.2016, 10, S. 1332-1342

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Towards personalized diagnostics via longitudinal study of the human plasma N-glycome

Hennig, René; Cajic, Samanta; Borowiak, Matthias; Hoffmann, Marcus; Kottler, Robert; Reichl, Udo; Rapp, Erdmann

In: Biochimica et biophysica acta / General subjects: BBA - Amsterdam [u.a.]: Elsevier, 1964, Bd. 1860.2016, 8, S. 1728-1738

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Site-specific O-glycosylation analysis of human blood plasma proteins

Hoffmann, Marcus; Marx, Kristina; Reichl, Udo; Wuhrer, Manfred; Rapp, Erdmann

In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, 2002, Bd. 15.2016, 2, S. 624-641

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A membrane-based purification process for cell culture-derived influenza A virus

Weigel, Thomas; Solomaier, Thomas; Wehmeyer, Sebastian; Peuker, Alessa; Wolff, Michael W.; Reichl, Udo

In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 220.2016, S. 12-20

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Purification of cell culture-derived influenza virus using simulated moving bed chromatography

Kröber, Tina; Reichl, Udo; Seidel-Morgenstern, Andreas

In: Magdeburg, 2016, XX, 171 Seiten, Illustrationen, Diagramme, 30 cm

Proteomanalytik der Adaption tierischer Zelllinien an Suspensionswachstum und optimierte Medien im Kontext der Impfstoffproduktion

Pech, Sabine; Reichl, Udo

In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2016, XXIV, 192, lxxvii Seiten, Illustrationen, Diagramme, 30 cm

Etablierung und Anwendung einer durchflusszytometrischen Methode für die Vitalitätsbestimmung von P. aeruginosa, B. cepacia und S. aureus in Mischkulturen

Rüger, Marc; Reichl, Udo

In: Magdeburg, 2016, XIV, 161, viii Blätter, Illustrationen

Novel computational methods for the analysis and interpretation of MS/MS data in metaproteomics

Muth, Thilo; Weiß, Helmut; Reichl, Udo

In: Magdeburg, 2016, XVI, 197 Seiten, Illustrationen

Modellbasierte Bestimmung von Interventionsstrategien zur Optimierung der Produktion von Biokraftstoffen in Cyanobakterien

Erdrich, Philipp; Reichl, Udo; Kienle, Achim

In: Magdeburg, 2016, xx, 158 Seiten, Illustrationen

The MetaProteomeAnalyzer - a powerful open-source software suite for metaproteomics data analysis and interpretation

Muth, Thilo; Behne, Alexander; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Hoffmann, Marcus; Lehtevä, Miro; Reichl, Udo; Martens, Lennart; Rapp, Erdmann

In: Journal of proteome research - Washington, DC : ACS Publications, Bd. 14 (2015), Heft 3, S. 1557-1565

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Comparison of influenza virus particle purification using magnetic sulfated cellulose particles with an established centrifugation method for analytics

Serve, Anja; Pieler, Michael Martin; Benndorf, Dirk; Rapp, Erdmann; Wolff, Michael Werner; Reichl, Udo

In: Analytical chemistry - Columbus, Ohio : American Chemical Society, Bd. 87 (2015), Heft 21, S. 10708-10711

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Metaproteomics of activated sludge from a wastewater treatment plant - a pilot study

Püttker, Sebastian; Kohrs, Fabian; Benndorf, Dirk; Heyer, Robert; Rapp, Erdmann; Reichl, Udo

In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3596-3601

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Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities

Kohrs, Fabian; Wolter, Sophie; Benndorf, Dirk; Heyer, Robert; Hoffmann, Marcus; Rapp, Erdmann; Bremges, Andreas; Sczyrba, Alexander; Schlüter, Andreas; Reichl, Udo

In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3585-3589

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Metaproteomics of complex microbial communities in biogas plants

Heyer, Robert; Kohrs, Fabian; Reichl, Udo; Benndorf, Dirk

In: Microbial biotechnology - Oxford : Wiley-Blackwell, Bd. 8 (2015), Heft 5, S. 749-763

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Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection

Heldt, Frank S.; Kupke, Sascha Young; Dorl, Sebastian; Reichl, Udo; Frensing, Timo

In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Vol. 6.2015, Art. 8938, insgesamt 12 S.

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Editorial: Can modern vaccine technology pursue the success of traditional vaccine manufacturing?

Grabherr, Reingard; Reichl, Udo

In: Biotechnology journal: BTJ : systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, Bd. 10.2015, 5, S. 657-658

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Community shifts in a well-operating agricultural biogas plant - how process variations are handled by the microbiome

Theuerl, Susanne; Kohrs, Fabian; Benndorf, Dirk; Maus, Irena; Wibberg, Daniel; Schlüter, Andres; Kausmann, Robert; Heiermann, Monika; Rapp, Erdmann; Reichl, Udo; Pühler, Alfred; Klocke, Michael

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 99 (2015), 18, S. 7791-7803

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Bioreactor concepts for cell culture-based viral vaccine production

Gallo-Ramírez, Lilí Esmeralda; Nikolay, Alexander; Genzel, Yvonne; Reichl, Udo

In: Expert review of vaccines - Abingdon, Oxon: Taylor & Francis, 2002, Bd. 14.2015, 9, S. 1181-1195

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Navigating through metaproteomics data - a logbook of database searching

Muth, Thilo; Kolmeder, Carolin A.; Salojärvi, Jarkko; Keskitalo, Salla; Varjosalo, Markku; Verdam, Froukje J.; Rensen, Sander S.; Reichl, Udo; Vos, Willem M.; Rapp, Erdmann; Martens, Lennart

In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3439-3453

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Colonic metaproteomic signatures of active bacteria and the host in obesity

Kolmeder, Carolin A.; Ritari, Jarmo; Verdam, Froukje J.; Muth, Thilo; Keskitalo, Salla; Varjosalo, Markku; Fuentes, Susana; Greve, Jan Willem; Buurman, Wim A.; Reichl, Udo; Rapp, Erdmann; Martens, Lennart; Palva, Airi; Salonen, Anne; Rensen, Sander S.; Vos, Willem M.

In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3544-3552

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Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension

Pech, Sabine; Benndorf, Dirk; Genzel, Yvonne; Scharfenberg, Klaus; Rapp, Erdmann; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, Bd. 33 (2015), 35, S. 4269-4280

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Exclusive decoration of simian immunodeficiency virus Env with high-mannose type N-glycans is not compatible with mucosal transmission in rhesus macaques

Karsten, Christina B.; Buettner, Falk F. R.; Cajic, Samanta; Nehlmeier, Inga; Neumann, Berit; Klippert, Antonina; Sauermann, Ulrike; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christiane; Pöhlmann, Stefan

In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 89.2015, 22, S. 11727-11733

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Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs

Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo

In: Virus research: an international journal of molecular and cellular virology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 213.2015, S. 90-99

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Infection dynamics and virus-induced apoptosis in influenza virus A infected adherent and suspension MDCK cells

Peschel, Britta; Reichl, Udo; Marwan, Wolfgang

In: Zugl.: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015: Aachen: Shaker, VI, 180 S., Ill., graph. Darst., 21 cm, 291 g - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; 44)

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Mathematical models of influenza A virus infection - from intracellular replication to virus growth in cell populations

Heldt, Frank Stefan; Frensing, Timo; Reichl, Udo

In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015, 2014, XX, 190 S., graph. Darst.

Population balance modeling of influenza A virus replication in MDCK cells during vaccine production

Müller, Thomas; Kienle, Achim; Reichl, Udo

In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, X, 127 S., graph. Darst.

Sample prefractionation with liquid isoelectric focusing enables in depth microbial metaproteome analysis of mesophilic and thermophilic biogas plants

Kohrs, Fabian; Heyer, Robert; Magnussen, A.; Benndorf, Dirk; Muth, Thilo; Behne, Alexander; Rapp, Erdmann; Kausmann, Robert; Heiermann, Monika; Klocke, Michael; Reichl, Udo

In: Anaerobe - London : Academic Press, Bd. 29 (2014), S. 59-67

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Impact of cultivation conditions on N-glycosylation of influenza virus A hemagglutinin produced in MDCK cell culture

Rödig, Jana; Rapp, Erdmann; Bohne, Jana; Kampe, Michael; Kaffka, Helene; Bock, Andreas; Genzel, Yvonne; Reichl, Udo

In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2014), Heft 6, S. 1691-1703

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Vaccine production - upstream processing with adherent or suspension cell lines

Genzel, Yvonne; Rödig, Jana; Rapp, Erdmann; Reichl, Udo

In: Animal Cell Biotechnology , 3rd ed. 2014 - Totowa, NJ : Humana Press , 2014, S. 371-393 - (Methods in Molecular Biology, Methods and Protocols; 1104)

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Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production

Frensing, Timo; Pflugmacher, Antje; Bachmann, Mandy; Peschel, Britta; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 98.2014, 21, S. 8999-9008

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Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological

Huffman, Jennifer E.; Pučić-Baković, Maja; Klarić, Lucija; Hennig, René; Selman, Maurice H. J.; Vučković, Frano; Novokmet, Mislav; Krištić, Jasminka; Borowiak, Matthias; Muth, Thilo; Polašek, Ozren; Razdorov, Genadij; Gornik, Olga; Plomp, Rosina; Theodoratou, Evropi; Wright, Alan F.; Rudan, Igor; Hayward, Caroline; Campbell, Harry; Deelder, André M.; Reichl, Udo; Aulchenko, Yurii S.; Rapp, Erdmann; Wuhrer, Manfred; Lauc, Gordan

In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 13.2014, S. 1598-1610

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Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media

Rehberg, M.; Rath, A.; Ritter, J. B.; Genzel, Y.; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 1, S. 385-397

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Biological methanation of hydrogen within biogas plants - a model-based feasibility study

Bensmann, Astrid; Hanke-Rauschenbach, R.; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Reichl, Udo; Sundmacher, Kai

In: Applied energy - Amsterdam [u.a.]: Elsevier Science, Bd. 134 (2014), S. 413-425

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Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor

Tapia Delgado, Felipe Ignacio; Vogel, Thomas; Genzel, Yvonne; Behrendt, Ilona; Hirschel, Mark; Gangemi, J. David; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 32.2014, 8, S. 1003-1011

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Species-specific viability analysis of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus in mixed culture by flow cytometry

Rüger, Marc; Ackermann, Mandy; Reichl, Udo

In: BMC microbiology - London: BioMed Central, Bd. 14.2014, Art. 56, insgesamt 15 S.

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A flow-through chromatography process for influenza A and B virus purification

Weigel, Thomas; Solomaier, Thomas; Peuker, Alessa; Pathapati, Trinath; Wolff, Michael W.; Reichl, Udo

In: Journal of virological methods - Amsterdam [u.a.]: Elsevier Science, Bd. 207.2014, S. 45-53

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The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis

Lohr, Verena; Hädicke, Oliver; Genzel, Yvonne; Jordan, Ingo; Büntemeyer, Heino; Klamt, Steffen; Reichl, Udo

In: BMC biotechnology - London: BioMed Central, Vol. 14.2014, Art. 72 insgesamt 14 S.

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Avidity of influenza virus: Model-based identification of adsorption kinetics from surface plasmon resonance experiments

Wang, Wenjing; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai

In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1326.2014, S. 125-129

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Flow cytometric viability assessment of lactic acid bacteria starter cultures produced by fluidized bed drying

Bensch, Gerald; Rüger, Marc; Wassermann, Magdalena; Weinholz, Susann; Reichl, Udo; Cordes, Christiana

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 11, S. 4897-4909

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High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells

Genzel, Yvonne; Vogel, Thomas; Buck, Johannes; Behrendt, Ilona; Vázquez Ramírez, Daniel; Schiedner, Gudrun; Jordan, Ingo; Reichl, Udo

In: Vaccine - Amsterdam: Elsevier, Bd. 32 (2014), 24, S. 2770-2781

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The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells

Rath, Alexander; Rehberg, Markus; Janke, Robert; Genzel, Yvonne; Scholz, Sebastian; Noll, Thomas; Rose, Thomas; Sandig, Volker; Reichl, Udo

In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 178.2014, S. 43-53

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Glycolysis is governed by growth regime and simple enzyme regulation in adherent MDCK cells

Rehberg, Markus; Ritter, Joachim B.; Reichl, Udo

In: PLoS Computational Biology: a new community journal - San Francisco, Calif: Public Library of Science, Vol. 10.2014, 10, Art. e1003885, insgesamt 16 S.

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Characterization of the avian designer cells AGE1.CR and AGE1.CR.plX considering growth, metabolism and production of influenza virus and Modified Vaccinia Virus Ankara (MVA)

Lohr, Verena; Reichl, Udo

In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, IX, 178 S., Ill., graph. Darst., 30 cm

Impact of cultivation conditions on N-glycosylation of influenza A virus hemagglutinin, on quasispecies composition, and on immunogenicity of virus preparations

Rödig, Jana Verena; Reichl, Udo

In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, XVII, 159, S44 Bl., graph. Darst.

Improving industrial antibody manufacturing processes using animal cell culture technology

Pohlscheidt, Michael; Reichl, Udo

In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Habil.-Schr., 2014, Getr. Zählung, Ill., graph. Darst., 30 cm

Large-Scale Networks in Engineering and Life Sciences

Benner, Peter; Findeisen, Rolf; Flockerzi, Dietrich; Reichl, Udo; Sundmacher, Kai

In: Cham: Birkhäuser, 2014, Online-Ressource (XIV, 388 p. 111 illus., 63 illus. in color, online resource) - (Modeling and Simulation in Science, Engineering and Technology; SpringerLink; Bücher; Springer eBook Collection; Mathematics and Statistics), ISBN: 978-3-319-08437-4

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Distributed modeling of human influenza a virus–host cell interactions during vaccine production

Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim

In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2013), Heft 8, S. 2252-2266

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Metaproteome analysis of the microbial communities in agricultural biogas plants

Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Rapp, Erdmann; Kausmann, Robert; Heiermann, Monika; Klocke, Michael; Reichl, Udo

In: New biotechnology - New York, NY [u.a.] : Elsevier, Bd. 30 (2013), Heft 6, S. 614-622

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Evaluating differences of metabolic performances - statistical methods and their application to animal cell cultivations

Hädicke, O.; Lohr, V.; Genzel, Y.; Reichl, Udo; Klamt, S.

In: Biotechnology & bioengineering. - New York, NY [u.a.] : Wiley, Bd. 110.2013, 10, S. 2633-2642

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PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia

Tung, Stephanie; Shi, Yonghong; Wong, Karry; Zhu, Fang; Gorczynski, Reg; Laister, Robert C.; Minden, Mark; Blechert, Anne-Kareen; Genzel, Yvonne; Reichl, Udo; Spaner, David E.

In: Blood. - Stanford, Calif : HighWire Press, Bd. 112.2013, 6, S. 969-980

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Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles

Frensing, Timo; Stefan, Frank; Pflugmacher, Antje; Behrendt, Ilona; Jordan, Ingo; Flockerzi, Dietrich; Genzel, Yvonne; Reichl, Udo

In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 8.2013, 9, Art. e72288, insgesamt 9 S.

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Proteomics in environmental and technical microbiology

Benndorf, Dirk; Reichl, Udo

In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 14.2013, 1, S. 27-46

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Development of a high-throughput glycoanalysis method for the characterization of oligosaccharides in human milk utilizing multiplexed capillary gel electrophoresis with laser-induced fluorescence detection

Kottler, Robert; Mank, Marko; Hennig, René; Müller-Werner, Beate; Stahl, Bernd; Reichl, Udo; Rapp, Erdmann

In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2323-2336

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Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals

Heldt, Frank S.; Frensing, Timo; Pflugmacher, Antje; Gröpler, Robin; Peschel, Britta; Reichl, Udo

In: PLoS Computational Biology: a new community journal/ Public Library of Science - San Francisco, Calif.: Public Library of Science, 2005, Bd. 9.2013, 11, Art. e1003372, insges. 13 S.

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glyXalign - high-throughput migration time alignment preprocessing of electrophoretic data retrieved via multiplexed capillary gel electrophoresis with laser-induced fluorescence detection-based glycoprofiling

Behne, Alexander; Muth, Thilo; Borowiak, Matthias; Reichl, Udo; Rapp, Erdmann

In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2311-2315

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CAP, a new human suspension cell line for influenza virus production

Genzel, Yvonne; Behrendt, Ilona; Rödig, Jana; Rapp, Erdmann; Kueppers, Claudia; Kochanek, Stefan; Schiedner, Gudrun; Reichl, Udo

In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 97 (2013), 1, S. 111-122, 2012

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Toward animal cell culturebased influenza vaccine design - viral hemagglutinin N-glycosylation markedly impacts immunogenicity

Hütter, Julia; Rödig, Jana; Höper, Dirk; Seeberger, Peter H.; Reichl, Udo; Rapp, Erdmann; Lepenies, Bernd

In: The journal of immunology - Bethesda, Md.: Soc., Bd. 190 (2013), 1, S. 220-230

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Elements in the development of a production process for modified vaccinia virus ankara

Jordan, Ingo; Lohr, Verena; Genzel, Yvonne; Reichl, Udo; Sandig, Volker

In: Microorganisms. - Basel : MDPI, Bd. 1.2013, 1, S. 100-121

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Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line

Peschel, B.; Frentzel, S.; Laske, T.; Genzel, Y.; Reichl, Udo

In: Vaccine. - Amsterdam : Elsevier, Bd. 31.2013, 48, S. 5693-5699

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Continuous purification of influenza virus using simulated moving bed chromatography

Kröber, T.; Wolff, M. W.; Hundt, B.; Seidel-Morgenstern, Andreas; Reichl, Udo

In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1307 (2013), S. 99-110

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Metagenome and metaproteome analyses of microbial communities in mesophilic biogas-producing anaerobic batch fermentations indicate concerted plant carbohydrate degradation

Hanreich, Angelika; Schimpf, Ulrike; Zakrzewski, Martha; Schlüter, Andreas; Benndorf, Dirk; Heyer, Robert; Rapp, Erdmann; Pühler, Alfred; Reichl, Udo; Klocke, Michael

In: Systematic and applied microbiology - München: Elsevier, Bd. 36 (2013), 5, S. 330-338

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